Paper Key : IRJ************347
Author: Shruti Santosh Gavali,Sujata V. Lambe
Date Published: 07 Jan 2025
Abstract
Curcuma longa, or turmeric, is a spice that has been used extensively for its therapeutic qualities in the ayurvedic medicine systems of South Asia, including China and India. Curcuma's primary constituent, curcuma, contains three curcumins, which give turmeric its various therapeutic and physical qualities. The current study examines the literature in a systematic manner about curcumin's anti-inflammatory properties in cancer therapy. Studies have revealed that curcumin is a very pleiotropic chemical that interacts with a wide range of molecular targets. According to a thorough review of the research, curcumin, turmeric's main active ingredient, has a major role in several forms of cancer. Curcumin's capacity to inhibit andor activate several intercellular transcription factors, which control protein expression and development, is primarily responsible for its anticancer potential. In this overview, the mechanism of action and effects are briefly covered. Curcumin is a tautomeric molecule that occurs as an enolic form in organic solvents and as a keto form in water. Epidemiological evidence suggests that consuming turmeric may reduce the risk of some cancers and have other positive biological effects on humans, however the results are not definitive. Curcumin, the active element in turmeric, has been widely studied for its anti-inflammatory, anti-ulcer, anti-diabetic, antiviral, antioxidant, wound healing, and anti-cancer effects. These advantages have been related to the biological benefits of turmeric.
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