Paper Key : IRJ************861
Author: Yerpude Tejas Vilas,Bankar Siddheshwar Dilip,Ingle Vaibhav Gajanan,Mrs. Dhonde S.n.,Dr. Kolhe S.d.
Date Published: 04 Dec 2024
Abstract
Diabetes mellitus, a global health concern, particularly prevalent in India, necessitates innovative treatment approaches. Bitter melon (Momordica charantia), renowned as "vegetable insulin," offers a promising natural solution due to its hypoglycemic properties. To enhance bioavailability and reduce gastrointestinal irritation, chewable lozenges present an ideal dosage form. These solid dosage forms, designed to dissolve slowly in the mouth, extend drug retention time, facilitating both local and systemic therapeutic effects. The unique combination of bitter melon's phytochemical richness and the advantages of lozenge formulation offers a potential strategy for managing diabetes mellitus. Numerous pre-clinical and clinical studies have supported the efficacy of bitter melon, and its incorporation into chewable lozenges can provide a convenient and effective treatment option.
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