Paper Key : IRJ************791
Author: Sanket Karale Niharika Tumade
Date Published: 05 Jan 2025
Abstract
Japanese encephalitis (JE) poses a critical public health challenge in Asia, characterized by complex viral transmission dynamics, significant neurological impacts, and persistent outbreaks. This review explores JEs epidemiological trends, molecular complexity, clinical presentations, and control strategies. The virus, primarily transmitted by Culex mosquitoes and amplified through animal reservoirs such as pigs and birds, thrives in agricultural landscapes, particularly rice paddies. While the majority of infections are asymptomatic, severe cases lead to debilitating neurological damage. Advanced diagnostic tools like RT-PCR and neuroimaging enhance disease management, while vaccination remains the cornerstone of prevention. Despite these measures, challenges in vector control, ecological factors, and genetic mutation rates complicate eradication efforts. A comprehensive, multidisciplinary approach is essential for tackling this enduring global health threat.
DOI Requested