Paper Key : IRJ************335
Author: Samadhan Balasaheb Kadlasakar,Ms. M. R. Deokar
Date Published: 19 Nov 2024
Abstract
Nanomedicine, a rapidly evolving field at the intersection of nanotechnology and medicine, has shown tremendous potential in revolutionizing the diagnosis, treatment, and prevention of diseases. This review paper provides a comprehensive overview of the principles, applications, and challenges associated with nanomedicines. We explore various nanocarrier systems, including liposomes, dendrimers, and polymeric nanoparticles, and their role in enhancing drug delivery, targeting specific tissues, and improving bioavailability (1). The paper discusses advancements in targeted therapy, where nanoparticles can deliver therapeutics directly to diseased cells, minimizing side effects and improving treatment efficacy (2). Furthermore, we examine the integration of nanomedicine with diagnostic techniques, such as imaging and biosensing, which enables early detection and monitoring of diseases (3).Despite the promising applications, the translation of nanomedicines from bench to bedside faces significant hurdles, including biocompatibility, regulatory challenges, and production scalability (4). The review emphasizes the importance of rigorous safety assessments and the establishment of clear regulatory guidelines to ensure the safe use of nanomedicines in clinical settings (5). Additionally, we highlight ongoing research aimed at addressing these challenges and advancing the field toward practical applications.In conclusion, while nanomedicines hold great promise for transforming healthcare, further research and collaboration among scientists, clinicians, and regulatory agencies are essential to unlock their full potential. This review aims to provide insights into the current state of nanomedicine, foster discussions on overcoming existing challenges, and encourage future research directions that can facilitate the development of effective nanomedicines for a wide range of diseases.