Paper Key : IRJ************924
Author: Alisha Rajesh Shirole,Tulika Bakshi
Date Published: 26 May 2024
Abstract
ABSTRACTMetabolic disorders, including obesity, type 2 diabetes, and cardiovascular diseases, pose significant challenges to global public health. Despite advancements in therapeutic approaches, effective management remains elusive. Resveratrol, a polyphenolic compound abundant in various dietary sources such as grapes, red wine, and berries, has emerged as a potential therapeutic agent for metabolic dysfunction. This abstract synthesizes findings from a comprehensive review of the literature, highlighting the diverse mechanisms through which resveratrol exerts its beneficial effects on metabolic health. These mechanisms encompass modulation of insulin sensitivity, regulation of lipid metabolism, attenuation of inflammation, and enhancement of mitochondrial function. Furthermore, preclinical and clinical studies have demonstrated the efficacy of resveratrol supplementation in ameliorating metabolic parameters and improving overall metabolic health in both animal models and human subjects. However, challenges such as bioavailability and dosing regimens warrant further investigation. Overall, this literature-based abstract provides a nuanced understanding of the therapeutic potential of resveratrol in the management of metabolic disorders, laying the foundation for future research and clinical interventions in this field.Keywords- Resveratrol, Diabetes, Grapes, anthocyanins.
DOI Requested