Paper Key : IRJ************961
Author: Adebawore Adefusisoye Adegalu
Date Published: 04 Nov 2024
Abstract
This study explores the synthesis, characterization, and antimicrobial evaluation of metal complexes of ampicillin. The complexes were synthesized and characterized using various analytical techniques, including UV-Vis spectroscopy, FTIR spectroscopy, and physical analysis. The solubility of the complexes was assessed in different solvents, providing insights into their physicochemical properties. Antimicrobial evaluation against both fungal and bacterial strains revealed that the metal complexes exhibited enhanced antimicrobial activity compared to free ampicillin. The results demonstrate the potential of metal complexation as a strategy to enhance the efficacy of antibiotics against microbial pathogens. Further research is warranted to elucidate the mechanisms underlying the enhanced antimicrobial activity of the metal complexes and to explore their potential applications in medicine and biotechnology.
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