Paper Key : IRJ************865
Author: Shivshankar Madhukar Nagrik,Shatrughna Uttam Nagrik,Vinod Chaware,Shalini Sudhakar Nagrik,Pallavi Nagesh Chavhan ,Dipali Ramesh Kedar,Kalyani Madhukar Shelke,Mayuri Ashok Rathod
Date Published: 02 Apr 2024
Abstract
Nanoscience and nanobiotechnology have revolutionized the exploration of bactericidal and fungicidal properties, particularly through the utilization of silver nanoparticles (AgNPs) known for their ancient antibacterial efficacy. This review paper delves into the synthesis methods of AgNPs, emphasizing physical, chemical, and biological approaches. Physical methods like evaporation-condensation and laser ablation are highlighted alongside chemical processes such as chemical reduction and micro-emulsion. Biological methods leveraging biological organisms like bacteria and plants are also discussed. The review elucidates the importance and applications of AgNPs in various industries, including their pivotal role in antibacterial treatments, water purification, and medical devices. The synthesis methods discussed are not only cost-effective and energy-efficient but also environmentally friendly, making them conducive to medicinal applications. Additionally, AgNPsapplications in biosensors for pathogen detection, anticancer agents, and wound healing are explored.Furthermore, the paper delves into characterization techniques crucial for understanding AgNPsproperties and their applications. Various methods such as UV-Visible spectrophotometry, scanning electron microscopy (SEM), and dynamic light scattering (DLS) are discussed for characterizing AgNPsmorphology, size, stability, and surface charge.The biological applications of AgNPs are also covered comprehensively, including their antifungal, antibacterial, antiviral, anti-inflammatory, anti-cancer, and anti-angiogenic properties. The mechanisms underlying AgNPsaction against pathogens and their potential in medical treatments are elucidated, offering insights into their diverse applications in healthcare, environmental protection, and material science. Overall, this review provides a comprehensive overview of AgNPs synthesis, characterization, and biological applications, highlighting their immense potential in various industries and medical fields.