Paper Key : IRJ************782
Author: Satpute Om Santosh,Gunjal Avdhut Vijay,Godage Pramod Sudam,Dighe Prasad Sahebrao ,Khemnar Mahesh Rajendra
Date Published: 02 Jul 2024
Abstract
Excessive mucous secretion in the respiratory tract is a common pathological feature in various respiratory disorders, including asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis. The aimed of this project is to developing formulation to decrease mucous secretion in the respiratory tract, thereby alleviating symptoms and improving the quality of life for affected individuals. Utilizing the knowledge, the project will explore potential therapeutic targets and interventions to modulate mucous secretion. Strategies may include pharmacological approaches targeting specific receptors or enzymes involved in mucin synthesis and secretion, as well as novel drug delivery systems to directly target mucin-producing cells within the respiratory tract. Furthermore This project proposes to formulate the formulation by using chemical constituent of Ajwain (Trachyspermum ammi) and ginger (Zingiber officinale) extracts in reducing mucous secretion in the respiratory tract. Both Ajwain and ginger have been traditionally used in various cultures for their medicinal properties, including their purported ability to alleviate respiratory symptoms. Ajwain and ginger contain active compounds such as thymol and gingerol, which have antiinflammatory and expectorant properties. Thymol in ajwain acts as a bronchodilator, helping to widen the airways and reduce congestion. Gingerol in ginger works as an expectorant, promoting the expulsion of mucus from the respiratory tract. Additionally, both herbs have antimicrobial properties that may help fight respiratory infections, further aiding in reducing mucous secretion. The outline of this formulation is to proposed methodology, which is assess the impact of Ajwain and ginger extracts on mucous production and secretion. This project seeks to providevaluable insights into the potential use of Ajwain and ginger extracts as natural therapeutics for managing respiratory conditions characterized by excessive mucous secretion. Overall, this project aims to contribute to the development of effective therapeutic strategies for reducing mucous secretion in the respiratory tract, thereby improving respiratory health and quality of life for individuals with respiratory disorders.