Paper Key : IRJ************974
Author: Rohini Uttam Jadhav,Pravin R.dighe
Date Published: 03 Apr 2025
Abstract
An introduction to chromatography is given throughout the work, emphasizing the division of components into stationary and mobile phases. It describes the parts of a chromatographic system and presents mass spectrometry as an accurate ion analysis method. The components of a mass spectrometer and developments in liquid chromatography-mass spectrometry (LCMS) technology are also covered in the text, with a focus on how well this technology combines the ability to detect mass spectrometry with the resolving power of liquid chromatography. Drug development procedures and structure elucidation investigations are said to benefit greatly from the use of LCMS, which provides data on the molecular weight, structure, identification, and quantity of sample components. There is also discussion of the significance of method validation and several factors for assessing liquid chromatographic research.
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