Paper Key : IRJ************370
Author: Ritesh Patil,Nilesh Chougule
Date Published: 01 Jul 2024
Abstract
An essential medicinal plant, Spilanthesacmella is found in tropical and subtropical regions, primarily in South America and India. It is commonly referred to as the "toothache plant," as it may both stimulate salivation and lessen the discomfort associated with toothaches. This plant has a variety of extracts and active metabolites that have beneficial pharmacological properties in different regions of the plant. According to a literature review, it possesses a variety of pharmacological actions, such as antimicrobial, antinociception, diuretic, vasorelaxant, anti-human immunodeficiency virus, antifungal, antipyretic, local anesthetic, bioinsecticide, anticonvulsant, antioxidant, aphrodisiac, analgesic, and pancreatic lipase inhibitor properties. The phytochemistry, pharmacology, toxicity, and traditional applications of this plant are all covered in detail in this paper. The toothache plant, Spilanthesacmella, has long been utilized in ayurvedic medicine for dental conditions. Numerous research on its phytochemicals have been published, based on its historical use in food and medicine. An overview and general description of the plant species, bioactive metabolites, and significant pharmacological activities, such as preparation, purification, and large-scale in vitro synthesis, are given in this review. The links between the bioactive chemicalsstructures and activities have been examined. It is possible to show that S. acmella has a wide range of bioactive qualities and is widely used in medicine, healthcare, cosmetics, and dietary supplements by taking into account data from the literature Being a nutritious food, it has a great therapeutic value and lots of room to grow.
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