Paper Key : IRJ************385
Author: Prashant Dubey ,Sonali Tambe,Dr. Rupali .r. Tasgaonkar
Date Published: 03 Jan 2025
Abstract
Albumin is an interesting carrier in the nanomedicine field due to its unique properties. First, it is the most abundant protein in plasma and has high biodegradability, biocompatibility, non-immunogenicity and safety in clinical use. Second, the chemical structure and conformation of albumin allow it to interact with a wide range of different drugs, potentially protecting them from elimination and metabolism in the body and thus increasing their efficacy. Pharmacokinetics. Finally, albumin can interact with receptors overexpressed in tissues and cells and provide specific functions for activation of disease sites without the need for the addition of specific ligands for the nano- carriers. This article highlights the power of endogenous proteins such as albumin as drug carriers, highlights the importance of drug carriers in biological processes and suggests possible future developments in the use of this drug.
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