Paper Key : IRJ************212
Author: Omkar Prakash Neharkar,Premanand Atmaram Nighojkar,Naitik Narendra Nawkhare
Date Published: 02 Dec 2024
Abstract
Calendula officinalis, commonly known as pot marigold, has been valued in traditional medicine for its versatile therapeutic properties, particularly in treating skin ailments. Rich in bioactive compounds such as carotenoids, flavonoids, and terpenoids, C. officinal is demonstrates anti-inflammatory, antimicrobial, antioxidant, and wound-healing activities. This review consolidates current findings on its phytochemistry and pharmacological applications, highlighting its benefits in dermatology, anti-HIV activity, diabetes management, cardiovascular health, and wound care. The molecular mechanisms underlying these effects, including cytokine modulation and growth factor promotion, support its efficacy in inflammation reduction, skin regeneration, and chronic disease management. Additionally, its role in commercial skincare, cosmetics, and adjunctive therapies for dermatitis, eczema, and acne showcases its potential in modern healthcare. However, caution is advised for individuals allergic to the Asteraceae family. This review underscores Calendulas therapeutic versatility and potential for safe and effective plant-based treatments
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