Paper Key : IRJ************661
Author: Banuchandra N
Date Published: 11 Jul 2024
Abstract
Sleep plays an important role in maintaining human health, In recent years research has more focused on the relation between sleep duration and the risk of developing various chronic diseases including type 2 diabetes mellitus. This review article aims to explore the relationship between short sleep duration which is typically defined as sleeping 3 to 4 hours per day and the risk of type 2 diabetes mellitus.Several underlying mechanisms potentially contribute to this association, including disruptions in glucose metabolism, insulin sensitivity, hormonal regulation (such as leptin and ghrelin). Sleep deprivation alters the balance of hormones, promoting increased food intake and reduced energy expenditure. Moreover, insufficient sleep impairs pancreatic beta-cell function and exacerbates systemic inflammation and oxidative stress, all of which contribute to insulin resistance and glucose intolerance. Behavioral factors associated with short sleep duration, such as irregular eating patterns and reduced physical activity, may further amplify the risk of T2DM. Additionally, individuals with inadequate sleep often experience alterations in circadian rhythms, which can disrupt metabolic processes and exacerbate insulin resistance.