Paper Key : IRJ************272
Author: Swapnil Suresh Arjun,Gite Shweta
Date Published: 16 Nov 2024
Abstract
Controlled-release systems are designed to manage the plasma concentration of drugs post administration through various routes. These systems enable the drug to be released in a predetermined manner over a specified duration, typically exhibiting zero-order kinetics. Ideally, the release rate from the dosage form should be the rate-limiting step for both drug absorption and its concentration at the target site. By reducing the frequency of daily dosing, controlled release formulations enhance patient compliance and therapeutic outcomes. This article discusses the ideal requirements, advantages, properties, and various approaches involved in the development of controlled-release formulations, highlighting their significance in improving drug delivery .