Paper Key : IRJ************728
Author: Shivaji M. Patil,Sakshi S. Gavali,Amruta D. Tavse,Sanjyot S. Kasture
Date Published: 11 Nov 2024
Abstract
The most popular cosmetic product is lipstick. According to research findings, the administration of different antioxidants may be able to prevent the harmful effects of lead and the production of oxidative stress.Red dragon fruit, or Hylocereuspolyrhizus, is commonly accessible in Myanmar and contains betacyanin and anthocyanin pigment, an antioxidant amaranth colorant. It is appropriate as a natural lipstick colorant . The goal of this research, in the capacity of a pharmacist, was to reduce the harmful effects of lipsticks by creating a natural lipstick that included various natural components and betacyanin pigment derived from H. polyrhizus.Lipstick was created by heating and combining ingredients in a homogenizer running at 12,000 rpm. Subsequently, the following parameters were assessed for quality: pH, melting point, surface irregularities, aging stability, scent stability, and antioxidant activity. As part of the safety examination, microbiological analysis, skin irritation testing, and lead content measurement were performed. Lipstick formulas using H. polyrhizusbetacyanin pigment are of a satisfactory caliber.The IC50 values for designed lipstick and standard ascorbic acid were 22.23 gml and 4.51 gml, respectively. In qualitative analysis, Staphylococcus aureus, E. coli, and Pseudomonas aeruginosa were not found in 0.5 g of formed lipsticks, and in quantitative analysis for microbiological control, there was no apparent colony in the lipstick. Additionally, the designed lipstick exhibited very little skin irritation and a lead content of only 2.9 ppm, which is within the permitted range. Consequently, lipstick containing H. polyrhizusbetacyanin pigment can be used as cosmeceutical.The most popular cosmetic product is lipstick. According to research findings, the administration of different antioxidants may be able to prevent the harmful effects of lead and the production of oxidative stress.Red dragon fruit, or Hylocereuspolyrhizus, is commonly accessible in Myanmar and contains betacyanin and anthocyanin pigment, an antioxidant amaranth colorant. It is appropriate as a natural lipstick colorant . The goal of this research, in the capacity of a pharmacist, was to reduce the harmful effects of lipsticks by creating a natural lipstick that included various natural components and betacyanin pigment derived from H. polyrhizus.Lipstick was created by heating and combining ingredients in a homogenizer running at 12,000 rpm. Subsequently, the following parameters were assessed for quality: pH, melting point, surface irregularities, aging stability, scent stability, and antioxidant activity. As part of the safety examination, microbiological analysis, skin irritation testing, and lead content measurement were performed. Lipstick formulas using H. polyrhizusbetacyanin pigment are of a satisfactory caliber.The IC50 values for designed lipstick and standard ascorbic acid were 22.23 gml and 4.51 gml, respectively. In qualitative analysis, Staphylococcus aureus, E. coli, and Pseudomonas aeruginosa were not found in 0.5 g of formed lipsticks, and in quantitative analysis for microbiological control, there was no apparent colony in the lipstick. Additionally, the designed lipstick exhibited very little skin irritation and a lead content of only 2.9 ppm, which is within the permitted range. Consequently, lipstick containing H. polyrhizusbetacyanin pigment can be used as cosmeceutical.
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