Paper Key : IRJ************978
Author: Mohd Adil Tahseen,Preeti Biswas,Anees Miyan
Date Published: 12 Nov 2024
Abstract
The traditional medicinal plant species Leptadenia reticulata is used to cure a broad range of illnesses, including cancer, dysentery, hematopoiesis, emaciation, coughing, dyspnoea, fever, burning sensation, night blindness, and TB. It is well-known in Ayurveda for its lactogenic, restorative, and revitalizing qualities. Numerous commercial herbal preparations, such as Speman, Envirocare, Calshakti, Antisept, and Chyawanprash, contain this plant as one of their main constituents. A variety of bioactive chemicals, including -amyrin, -amyrin, ferulic acid, luteolin, diosmetin, rutin, -sitosterol, stigmasterol, hentricontanol, a triterpene alcohol called simiarenol, apigenin, reticulin, deniculatin, and leptaculatin, are responsible for this herb's medicinal potential. A wide range of pharmacological activities, including antibacterial, anticancer, lactogenic, antioxidant, anti-implantation, anti-asthmatic, modulating, hepatoprotective, antifungal, antidiabetic, and anti-inflammatory properties, have been discovered in the plant. To support the traditional applications of L. reticulata with evidence-based data, many physiologically active chemicals have not yet been found, and the majority of biological investigations on the plant are limited to crude extracts. Due to habitat degradation, irresponsible harvesting, and overexploitation, L. reticulata is currently considered a vulnerable endangered plant. Its widespread spread has been spurred by the veterinary, pharmaceutical, and nutraceutical sectors growing demand. However, the paucity of information on its agronomical procedures and the unavailability of authentic planting material hinders its commercial cultivation. Biotechnological techniques including genetic transformation, cell culture, cryopreservation, and synthetic seed technology can aid in conservation and boost L. reticulata metabolite production.
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